Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.54 |
| ▸ | HTR2A | P28223 | 8/20 | 0.50 |
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938572 | 1.00 | HTR7 (0.54) | HTR7CHRM4HTR2AHTR2CGRIN2B | |
| SCHEMBL9391743 | 0.90 | HTR2A (0.52) | HTR7CHRM4HTR2AHTR2CGRIN2B | |
| SCHEMBL9393339 | 0.90 | HTR2A (0.52) | HTR7CHRM4HTR2AHTR2CGRIN2B | |
| Hydrochloric Acid SCHEMBL8684071 | 0.85 | HTR2B (0.58) | HTR7CHRM4HTR2AHTR2CGRIN2B | |
| Hydrochloric Acid SCHEMBL8684280 | 0.85 | HTR2B (0.58) | HTR7CHRM4HTR2AHTR2CGRIN2B | |
| SCHEMBL6651828 | 0.85 | HTR7 (0.69) | HTR7CHRM4HTR2AHTR2CGRIN2B | |
| SCHEMBL8683890 | 0.84 | HTR7 (0.55) | HTR7CHRM4HTR2AHTR2CGRIN2B | |
| SCHEMBL8938607 | 0.84 | HTR7 (0.54) | HTR7CHRM4HTR2AHTR2CGRIN2B | |
| Hydrochloric Acid SCHEMBL9393283 | 0.84 | HTR7 (0.68) | HTR7CHRM4HTR2AHTR2CGRIN2B | |
| Hydrochloric Acid SCHEMBL8938691 | 0.82 | HTR2A (0.56) | HTR7CHRM4HTR2AHTR2CGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538981-A | 5-HYDROXYTRYPTAMINE RECEPTOR ANTAGONIST ACTIVITY | ELI LILLY AND COMPANY (US) | 1996-07-23 | — | — | US | claimed |