Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938815 | 0.87 | TDP1 (0.57) | TDP1AKR1B10AKR1B1AKR1C4AKR1C3 | |
| Chlomethoxyfen SCHEMBL8538106 | 0.81 | TDP1 (0.68) | TDP1MAPK1MAPTALDH1A1SMN1; SMN2 | |
| Chlomethoxyfen SCHEMBL38653 | 0.81 | TDP1 (0.68) | TDP1MAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8938800 | 0.81 | PNLIP (0.44) | TDP1AKR1C3AKR1C2MAPK1MAPT | |
| SCHEMBL28189382 | 0.81 | TDP1 (0.63) | TDP1MAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10857754 | 0.79 | TDP1 (0.62) | TDP1MAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9117636 | 0.79 | MAPT (0.62) | TDP1MAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10881383 | 0.79 | TDP1 (0.61) | TDP1MAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11135704 | 0.79 | TDP1 (0.61) | TDP1MAPK1MAPTLMNAMEN1 | |
| SCHEMBL9759376 | 0.79 | TDP1 (0.61) | TDP1MAPK1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484762-A | Aryloxy-n-(substituted phenyl) benzotriazole herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-16 | — | — | US | disclosed |