Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | PPOX | P50336 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938811 | 0.87 | TDP1 (0.59) | TDP1MEN1KMT2AAKR1B1AKR1C4 | |
| SCHEMBL8938814 | 0.86 | AKR1B1 (0.44) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10597469 | 0.84 | TDP1 (0.64) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10712751 | 0.84 | TDP1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11049633 | 0.83 | TDP1 (0.69) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL8938808 | 0.83 | MAPT (0.47) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL29938725 | 0.82 | TDP1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11247283 | 0.82 | TDP1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10847509 | 0.81 | TDP1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10850280 | 0.81 | TDP1 (0.62) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484762-A | Aryloxy-n-(substituted phenyl) benzotriazole herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-16 | — | — | US | disclosed |