SCHEMBL8938857

SCHEMBL8938857

COc1ccc2c(c1)CCC1CCc3cc(OC)c(OC)cc3C21

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
SRD5A1 P18405 2/20 0.44
KMT2A Q03164 1/20 0.44
HTR2C P28335 1/20 0.43
DRD2 P14416 1/20 0.43
DRD3 P35462 1/20 0.43
ABCB1 P08183 1/20 0.43
CHRNA7 P36544 1/20 0.43
SLC6A9 P48067 1/20 0.43
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43
DRD1 P21728 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8938904 0.94 DRD2 (0.44) CYP19A1CA1CA2SRD5A1KMT2A
SCHEMBL11238073 0.73 CHRNB2 (0.59) CYP19A1CA1CA2SRD5A1KMT2A
SCHEMBL8938889 0.73 KMT2A (0.52) KMT2A
SCHEMBL8068811 0.73 HTR2C (0.64) CYP19A1SRD5A1HTR2CDRD2DRD3
SCHEMBL31525384 0.73 HTR2C (0.64) CYP19A1SRD5A1HTR2CDRD2DRD3
SCHEMBL16944438 0.73 HTR2C (0.64) CYP19A1SRD5A1HTR2CDRD2DRD3
SCHEMBL14439395 0.72 CYP19A1 (0.50) CYP19A1CA1CA2SRD5A1HTR2C
SCHEMBL5498315 0.71 CYP19A1 (0.52) CYP19A1SRD5A1HTR2CDRD2DRD3
SCHEMBL22516687 0.71 CYP19A1 (0.52) CYP19A1SRD5A1HTR2CDRD2DRD3
SCHEMBL30563632 0.71 DRD2 (0.58) CYP19A1SRD5A1HTR2CDRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543298-A ADDING SPECIFIED COMPOUND TO LIQUID SAMPLE, MEASURING RATE OF AUTOOXIDATION SPECTROPHOTOMETRICALLY OXIS INTERNATIONAL S.A. (FR) 1996-08-06 US disclosed
EP-0625209-B1 METHOD FOR ASSAYING THE SOD ACTIVITY BY USING A SELF- OXIDIZABLE COMPOUND NECESSARY FOR ITS IMPLEMENTATION, SELF- OXIDIZABLE COMPOUNDS AND PREPARATION THEREOF OXIS INT SA (FR) 1996-07-17 EP disclosed
WO-1993011258-A1 METHOD FOR ASSAYING THE SOD ACTIVITY BY USING A SELF-OXIDIZABLE COMPOUND NECESSARY FOR ITS IMPLEMENTATION, SELF-OXIDIZABLE COMPOUNDS AND PREPARATION THEREOF BIOXYTECH (FR) 1993-06-10 WO disclosed