SCHEMBL8938907

SCHEMBL8938907

CCCCCOc1ccc(N)c(Nc2ccc(OC)cc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.51
GAA P10253 3/20 0.51
MAPT P10636 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 2/20 0.51
THRB P10828 2/20 0.51
RECQL P46063 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
HTT P42858 2/20 0.51
ALDH1A1 P00352 2/20 0.51
MMP14 P50281 1/20 0.51
TSHR P16473 2/20 0.44
NR4A1 P22736 1/20 0.44
UNG P13051 2/20 0.43
NPC1 O15118 2/20 0.43
MAPK1 P28482 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PPARG P37231 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7717777 0.88 TSHR (0.47) RAB9AGAAMAPTKDM4ETDP1
SCHEMBL8885417 0.86 MAPT (0.56) RAB9AGAAMAPTMEN1KMT2A
SCHEMBL4924540 0.82 MAPT (0.67) RAB9AGAAMAPTMEN1KMT2A
SCHEMBL14280666 0.80 KMT2A (0.47) RAB9AGAAMAPTMEN1KMT2A
SCHEMBL8938847 0.79 MAPT (0.54) RAB9AGAAMAPTMEN1KMT2A
SCHEMBL8962083 0.78 LMNA (0.58) RAB9AGAAMAPTMEN1KMT2A
SCHEMBL14463399 0.77 MAPK1 (0.40) RAB9AGAAMAPTMEN1KMT2A
SCHEMBL19350739 0.76 NR4A1 (0.65) RAB9AGAAMAPTMEN1KMT2A
SCHEMBL2213702 0.75 AKR1C3 (0.45) GAAMAPTMEN1KMT2AKDM4E
SCHEMBL4921551 0.75 UNG (0.45) RAB9AGAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484762-A Aryloxy-n-(substituted phenyl) benzotriazole herbicidal agents AMERICAN CYANAMID COMPANY (US) 1996-01-16 US disclosed