Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.50 |
| ▸ | UNG | P13051 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943853 | 0.81 | UNG (0.49) | UNGGAANPC1RAB9ANR5A1 | |
| SCHEMBL11470886 | 0.79 | NR5A1 (0.63) | TSHRUNGPLA2G4BNPC1RAB9A | |
| SCHEMBL1128464 | 0.79 | NR5A1 (0.63) | TSHRUNGPLA2G4BNPC1RAB9A | |
| SCHEMBL8962079 | 0.79 | NR5A1 (0.63) | TSHRUNGPLA2G4BNPC1RAB9A | |
| SCHEMBL8938907 | 0.78 | RAB9A (0.51) | LMNATSHRHTTSMN1; SMN2EGFR | |
| SCHEMBL8943895 | 0.78 | UNG (0.46) | HTTUNGGAAL3MBTL1ALDH1A1 | |
| SCHEMBL8944395 | 0.77 | MAPT (0.52) | LMNAHTTEGFRERBB3KMT2A | |
| SCHEMBL8324472 | 0.77 | NPC1 (0.64) | TSHRUNGGAAL3MBTL1NPC1 | |
| SCHEMBL8943737 | 0.76 | LTA4H (0.46) | LMNATSHRHTTSMN1; SMN2UNG | |
| SCHEMBL8944010 | 0.76 | MAPT (0.53) | LMNAHTTEGFRERBB3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512950-B1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | claimed |
| EP-0512950-A1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | claimed |
| US-5160647-A | High temperature lubricants, heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1992-11-03 | — | — | US | claimed |
| EP-0512950-B1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | disclosed |
| US-5244953-A | Polymers, oxidation and heat resistance | CIBA-GEIGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0512950-A1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-5160647-A | High temperature lubricants, heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1992-11-03 | — | — | US | disclosed |