SCHEMBL8939116

SCHEMBL8939116

COc1cc(OC)nc(Oc2cccc(Cl)c2C(=O)O)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.60
ALDH1A1 P00352 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9873475 0.99 NPSR1 (0.59) NPSR1ALDH1A1SMN1; SMN2
Isopropylamine SCHEMBL9871415 0.94 NPSR1 (0.58) NPSR1
Bispyribac SCHEMBL65725 0.90 CA12 (0.56) NPSR1ALDH1A1SMN1; SMN2
Bispyribac SCHEMBL4895772 0.90 CA12 (0.56) NPSR1ALDH1A1SMN1; SMN2
SCHEMBL8801724 0.89 ALDH1A1 (0.63) NPSR1ALDH1A1SMN1; SMN2
Bispyribac SCHEMBL20723830 0.89 KDM4E (0.57) NPSR1ALDH1A1
Bispyribac SCHEMBL9195440 0.89 CA12 (0.54) NPSR1ALDH1A1SMN1; SMN2
Bispyribac SCHEMBL238471 0.89 CA12 (0.54) NPSR1ALDH1A1SMN1; SMN2
Bispyribac SCHEMBL2114791 0.89 CA12 (0.54) NPSR1ALDH1A1SMN1; SMN2
SCHEMBL9045943 0.88 NPSR1 (0.62) NPSR1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0249708-B1 2-PHENOXYPYRIMIDINE DERIVATIVE AND HERBICIDAL COMPOSITIONS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-03-11 EP claimed
US-4900352-A 2-Phenoxypyimidine derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-02-13 US claimed
EP-0249708-A1 2-Phenoxypyrimidine derivative and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-12-23 EP claimed
JP-1175974-A None JP disclosed
JP-7149735-A None JP disclosed
US-5494888-A ACETOLACTATE SYNTHASE INHIBITOR LUCKY LTD. (KR) 1996-02-27 US disclosed
US-5494888-A ACETOLACTATE SYNTHASE INHIBITOR LUCKY LTD. (KR) 1996-02-27 US disclosed
EP-0287072-B1 2-Phenoxypyrimidine derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO (JP) 1995-07-05 EP disclosed
JP-H07149735-A PYRIMIDINYL OXYBENZOIC ACID DERIVATIVE, ITS PRODUCTION, AND USE THEREOF AS HERBICIDE LUCKY CO LTD 1995-06-13 JP disclosed
CN-1101345-A Novel herbicidal pyrimidine derivatives having alpha-carbonylimino structure, process for preparation and use as herbicides thereof LUCKY LTD (KR) 1995-04-12 CN disclosed
EP-0287079-B1 2-Phenoxypyrimidine derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO (JP) 1994-10-12 EP disclosed
EP-0426476-A1 Pyrimidine derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-08 EP disclosed
US-4985066-A 2-phenoxypyrimidine derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-01-15 US disclosed
US-4946495-A 2-phenoxypyrimidine derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-08-07 US disclosed
US-4900352-A 2-Phenoxypyimidine derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-02-13 US disclosed
US-4889552-A 2-Phenoxypyrimidine derivative and herbidical composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-12-26 US disclosed
JP-H01175974-A 2-PHENOXYPYRIMIDINE DERIVATIVE AND HERBICIDE KUMIAI CHEM IND CO LTD 1989-07-12 JP disclosed
EP-0287072-A2 2-Phenoxypyrimidine derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-10-19 EP disclosed
EP-0287079-A2 2-Phenoxypyrimidine derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-10-19 EP disclosed
EP-0249708-A1 2-Phenoxypyrimidine derivative and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-12-23 EP disclosed