Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL6035482 | 0.89 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11119130 | 0.89 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL7198587 | 0.89 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL9227122 | 0.89 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL700688 | 0.87 | TSHR (0.59) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL75014 | 0.87 | THRB (0.55) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL5968810 | 0.85 | ALDH1A1 (0.51) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9788891 | 0.85 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28540434 | 0.85 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| Ethylene SCHEMBL28333180 | 0.85 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073529-A2 | Preparation of sequential polymers and use thereof in coating compositions and as thickening agents | ROHM AND HAAS COMPANY (US) | 1983-03-09 | — | — | EP | claimed |
| US-5527613-A | CARBOXYLIC ACID OR ANHYDRIDE AND ETHYLENICALLY UNSATURATED MONOMERS; CONTROL RELEASE DEVICES FOR TARGET COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| US-5510422-A | FORMING SHELL AND CORE POLYMERIC PARTICLES HAVING MICROVOIDS BY NEUTRALIZING CORE CAUSING THE SHELL TO EXPLODE IN A CONTROLLED FASHION | ROHM AND HAAS COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| US-5304707-A | Neutralizing shell-core polymers so as to swell and absorb aqueous waste | ROHM AND HAAS COMPANY (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0315462-B1 | Method of solidification and encapsulation using core-shell polymer particles | ROHM & HAAS (US) | 1994-01-12 | — | — | EP | disclosed |
| EP-0565244-A1 | Polymeric particles | ROHM AND HAAS COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |
| EP-0315462-A2 | Method of solidification and encapsulation using core-shell polymer particles | ROHM AND HAAS COMPANY (US) | 1989-05-10 | — | — | EP | disclosed |