Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19458668 | 0.87 | KDM4E (0.60) | KDM4EKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL9953483 | 0.86 | KDM4E (0.59) | KDM4EKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL19458858 | 0.86 | KDM4E (0.59) | KDM4EKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL450012 | 0.83 | LMNA (0.58) | KDM4EKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL4846755 | 0.82 | MMP3 (0.65) | ALDH1A1MMP3HDAC1HDAC2MMP2 | |
| SCHEMBL8670844 | 0.82 | MMP3 (0.69) | KDM4EALDH1A1PTGDR2MMP3HDAC1 | |
| SCHEMBL4408915 | 0.81 | HDAC1 (0.66) | ALDH1A1MMP3HDAC1HDAC2MMP2 | |
| SCHEMBL1274377 | 0.81 | HDAC1 (0.66) | ALDH1A1MMP3HDAC1HDAC2MMP2 | |
| SCHEMBL8939365 | 0.81 | IRAK4 (0.39) | KDM4EALDH1A1PTGDR2FFAR4MMP2 | |
| SCHEMBL6743567 | 0.81 | KDM4E (0.46) | KDM4EKMT2AGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498363-A | Electrorheological fluid | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1996-03-12 | — | — | US | disclosed |