SCHEMBL8939441

SCHEMBL8939441

CCCCOc1cccc(O)c1CC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
CNR1 P21554 7/20 0.48
CNR2 P34972 7/20 0.48
PTPN1 P18031 1/20 0.47
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
JAK2 O60674 1/20 0.46
GAA P10253 1/20 0.46
MCHR1 Q99705 1/20 0.43
LTB4R Q15722 1/20 0.41
LTA4H P09960 1/20 0.41
NR5A1 Q13285 1/20 0.41
MEN1 O00255 1/20 0.41
NR1I2 O75469 1/20 0.41
CHRM2 P08172 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADRA2A P08913 1/20 0.41
OPRK1 P41145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17318047 0.93 CNR1 (0.55) CNR1CNR2PTPN1LMNAMAPT
SCHEMBL10355485 0.88 CNR1 (0.56) CYP1A2CYP2C9CYP2C19CNR1CNR2
SCHEMBL28322025 0.86 CNR1 (0.62) CYP1A2CYP2C9CYP2C19CNR1CNR2
SCHEMBL28669809 0.85 CNR1 (0.45) CNR1CNR2PTPN1LMNAMAPT
SCHEMBL30356524 0.84 ESR1 (0.48) CYP1A2CYP2C9CYP2C19CNR1CNR2
SCHEMBL11776675 0.83 MAPT (0.44) LMNAMAPTJAK2GAAMEN1
SCHEMBL67765 0.83 CYP1A2 (0.53) CYP1A2CYP2C9CYP2C19PTPN1LMNA
SCHEMBL11536830 0.83 LTB4R (0.54) MAPTLTB4R
SCHEMBL2849947 0.82 CNR2 (0.46) CYP1A2CYP2C9CYP2C19CNR1CNR2
SCHEMBL8936709 0.81 CNR1 (0.67) CNR1CNR2LMNAMAPTLTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705239-A4 PROCESS FOR PREPARING PHENETHANOL ETHERS HOECHST CELANESE CORP (US) 1996-08-21 EP disclosed
EP-0705239-A1 PROCESS FOR PREPARING PHENETHANOL ETHERS HOECHST CELANESE CORPORATION (US) 1996-04-10 EP disclosed
WO-1995000467-A1 PROCESS FOR PREPARING PHENETHANOL ETHERS HOECHST CELANESE CORPORATION (US) 1995-01-05 WO disclosed