Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 8/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939441 | 0.83 | CYP1A2 (0.49) | LTB4RMAPT | |
| SCHEMBL17318047 | 0.80 | CNR1 (0.55) | MAPT | |
| SCHEMBL11532707 | 0.80 | PPARD (0.54) | LTB4RLTB4R2PPARD | |
| SCHEMBL1842242 | 0.79 | HTR1A (0.47) | LTB4RLTB4R2PPARD | |
| SCHEMBL7999552 | 0.78 | PPARD (0.60) | LTB4RLTB4R2PPARDMAPTHPGD | |
| SCHEMBL27485493 | 0.77 | PPARD (0.56) | LTB4RLTB4R2PPARDMAPTHPGD | |
| SCHEMBL17961069 | 0.76 | PPARD (0.55) | LTB4RLTB4R2PPARDMAPTHPGD | |
| SCHEMBL74512 | 0.76 | PPARD (0.54) | LTB4RLTB4R2PPARDMAPTHPGD | |
| SCHEMBL5705647 | 0.76 | GABRA1 (0.46) | — | |
| SCHEMBL28669809 | 0.76 | CNR1 (0.45) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133889-A | ANAPHYLAXIS ANTAGONISTS | FISONS, LTD. (GB) | 1979-01-09 | — | — | US | disclosed |