Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.59 |
| ▸ | CTSB | P07858 | 4/20 | 0.59 |
| ▸ | CTSK | P43235 | 4/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171386 | 0.87 | CTSS (0.56) | CTSSCTSBCTSKCTSLACE | |
| SCHEMBL1032021 | 0.87 | CTSS (0.56) | CTSSCTSBCTSKCTSLACE | |
| SCHEMBL7060490 | 0.87 | CTSS (0.56) | CTSSCTSBCTSKCTSLACE | |
| SCHEMBL29850361 | 0.87 | TACR1 (0.61) | CTSSCTSBCTSKTACR1CTSL | |
| SCHEMBL8939478 | 0.86 | TACR1 (0.56) | CTSSCTSBCTSKTACR1CTSL | |
| SCHEMBL23085808 | 0.86 | LCK (0.46) | CTSSCTSBCTSKTACR1CTSL | |
| SCHEMBL23085810 | 0.86 | LCK (0.46) | CTSSCTSBCTSKTACR1CTSL | |
| SCHEMBL30423083 | 0.85 | ABCB1 (0.49) | CTSSCTSBCTSKPTPN1CTSL | |
| SCHEMBL3750286 | 0.84 | CTSS (0.55) | CTSSCTSBCTSKCTSLACE | |
| SCHEMBL10723853 | 0.84 | CTSS (0.55) | CTSSCTSBCTSKCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563132-B1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES | BLACK JAMES FOUNDATION (GB) | 1996-02-07 | — | — | EP | disclosed |
| US-5486597-A | GASTRIN ANTAGONIST AS ANTISECRETORY AGENTS OF GASTRIC JUICE FOR STOMACH CANCER | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |
| WO-1992011284-A1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES | THE JAMES BLACK FOUNDATION LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |