SCHEMBL3750286

SCHEMBL3750286

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSS P25774 6/20 0.55
CTSK P43235 5/20 0.55
LY96 Q9Y6Y9 1/20 0.46
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
AKT1 P31749 1/20 0.44
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43
ACE P12821 1/20 0.43
SCN9A Q15858 1/20 0.42
KLK5 Q9Y337 1/20 0.42
EPHX2 P34913 1/20 0.42
ITGA4 P13612 1/20 0.42
ITGB7 P26010 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10723853 1.00 CTSS (0.55) CTSSCTSKLY96CTSLCTSB
SCHEMBL19234621 0.91 PPARG (0.46) CTSSCTSKCTSLCTSBAKT1
SCHEMBL7063222 0.90 CACNA1B (0.48) CTSSCTSKCTSLCTSBAKT1
SCHEMBL18522552 0.90 CTSS (0.56) CTSSCTSKCTSLCTSBAKT1
SCHEMBL1032021 0.90 CTSS (0.56) CTSSCTSKCTSLCTSBAKT1
SCHEMBL3171386 0.90 CTSS (0.56) CTSSCTSKCTSLCTSBAKT1
SCHEMBL7060490 0.90 CTSS (0.56) CTSSCTSKCTSLCTSBAKT1
SCHEMBL30423083 0.89 ABCB1 (0.49) CTSSCTSKCTSLCTSBAKT1
SCHEMBL23085808 0.88 LCK (0.46) CTSSCTSKCTSLCTSBAKT1
SCHEMBL23085810 0.88 LCK (0.46) CTSSCTSKCTSLCTSBAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN claimed
US-5290576-A Antitumor polypeptide derivatives with iodine PLIVA FARMACEUTSKA (HR) 1994-03-01 US claimed
US-12612420-B2 Arginase inhibitors and methods of use thereof MOLECURE S.A. (PL) 2026-04-28 US disclosed
CN-119119173-A Kyotrophin synthesis method 湖北泓肽生物科技有限公司 2024-12-13 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
EP-4267590-A1 ARGINASE INHIBITORS AND METHODS OF USE THEREOF ONCOARENDI THERAPEUTICS S.A. (PL) 2023-11-01 EP disclosed
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2008022786-A1 AMINOACYL PRODRUG DERIVATIVES AND MEDICAMENTS FOR TREATMENT OF THROMBOEMBOLIC DISORDERS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-02-28 WO disclosed
US-20030130272-A1 Anthracene derivatives as anti-cancer agents BTG INTERNATIONAL LIMITED (GB) 2003-07-10 US disclosed
EP-1244624-A1 ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS BTG INTERNATIONAL LIMITED (GB) 2002-10-02 EP disclosed
WO-2001044190-A1 ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS BTG INTERNATIONAL LIMITED (GB) 2001-06-21 WO disclosed
US-5939279-A BLOCKING ATTACHMENT OF BACTERIA TO INTESTINAL EPITHELIAL BRUSH BORDER CELLS BY CONTACTING CELLS WITH OLIGOSACCHARIDE WITH MORE THAN 6 MANNOSE RESIDUES; PROPHYLAXIS AGAINST ENTEROBACTER CLOACAE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 1999-08-17 US disclosed
EP-0838471-A1 PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST SAGAMI CHEMICAL RESEARCH CENTER (JP) 1998-04-29 EP disclosed
EP-0169812-B1 PHOSPHATIDYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1989-08-23 EP disclosed
US-4788182-A VIRICIDES CIBA-GEIGY CORPORATION (US) 1988-11-29 US disclosed
EP-0169812-A1 Phosphatidyl compounds, process for their preparation and their use CIBA-GEIGY AG (CH) 1986-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130272-A1 Anthracene derivatives as anti-cancer agents TOP2B, TOP1, TOP2A CTSS 2690/4885CTSK 2190/4885LY96 1420/4885
US-12612420-B2 Arginase inhibitors and methods of use thereof ARG1, ARG2, ARGLU1 CTSS 628/4885CTSK 1074/4885LY96 1362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.