SCHEMBL8939826

SCHEMBL8939826

FC(F)=C(F)OCC(F)(F)C(F)F

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
POLB P06746 2/20 0.34
GAA P10253 1/20 0.34
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 2/20 0.31
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4619545 0.82 TSHR (0.33) TSHRPOLBGAAMEN1KMT2A
SCHEMBL4619549 0.82 TSHR (0.33) TSHRPOLBGAAMEN1KMT2A
SCHEMBL21925296 0.74
SCHEMBL8939861 0.74 TSHR (0.35) TSHRMEN1KMT2ALMNANPSR1
SCHEMBL546039 0.74 HTT (0.44)
SCHEMBL308634 0.73 TSHR (0.41) TSHRPOLBGAAMEN1KMT2A
SCHEMBL27702485 0.73 POLB (0.36) TSHRPOLBGAAMEN1KMT2A
SCHEMBL308635 0.71 LMNA (0.43) TSHRPOLBGAAMEN1KMT2A
SCHEMBL27220786 0.71 TSHR (0.41) TSHRPOLBGAAMEN1KMT2A
SCHEMBL25858052 0.71 HTT (0.43) TSHRPOLBGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661329-A Purification method for obtaining high-purity hydrofluoroether 山东华氟化工有限责任公司 2025-03-21 CN claimed
CN-119661329-A Purification method for obtaining high-purity hydrofluoroether 山东华氟化工有限责任公司 2025-03-21 CN disclosed
US-5536885-A Production of perfluoro(alkyl vinyl ethers) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-16 US disclosed
EP-0222157-B1 RESIN COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-12-30 EP disclosed
US-4886862-A MOISTURE-CURABLE SILYL-GROUP CONTAINING COPOLYMER OF A FLUOROALKYL PERVINYL ETHER AND A VINYL CARBOXYLATE, CATALYST AND SOLVENT; PAINTS; COATINGS, WEATHERPROOFING; HARDNESS DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-12-12 US disclosed
EP-0222157-A2 Resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-05-20 EP disclosed