SCHEMBL308635

SCHEMBL308635

O=C(O)OCC(F)(F)C(F)F

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
POLB P06746 2/20 0.41
TSHR P16473 2/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 4/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
NPSR1 Q6W5P4 3/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL308634 0.83 TSHR (0.41) LMNAPOLBTSHRGAATDP1
SCHEMBL2887866 0.82 HTT (0.35) LMNATSHRALDH1A1HTT
SCHEMBL25858052 0.81 HTT (0.43) LMNAPOLBTSHRGAATDP1
SCHEMBL27220786 0.81 TSHR (0.41) LMNAPOLBTSHRGAATDP1
SCHEMBL2536484 0.79 POLB (0.43) LMNAPOLBTSHRGAATDP1
SCHEMBL2536347 0.79 GAA (0.50) LMNAPOLBTSHRGAATDP1
SCHEMBL25981449 0.79 POLB (0.43) LMNAPOLBTSHRGAATDP1
SCHEMBL4397557 0.79 TSHR (0.40) LMNAPOLBTSHRGAATDP1
SCHEMBL13280672 0.79 TSHR (0.40) LMNAPOLBTSHRGAATDP1
SCHEMBL27903554 0.79 LMNA (0.41) LMNAPOLBTSHRGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025131951-A1 LITHIUM SECONDARY BATTERY WITH HIGH ENERGY DENSITY AND SAFETY SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2025-06-26 WO claimed
US-20170187071-A1 LITHIUM BATTERY ELECTROLYTE SOLUTION CONTAINING ETHYL (2,2,3,3-TETRAFLUOROPROPYL) CARBONATE DOW GLOBAL TECHNOLOGIES LLC 2017-06-29 US claimed
US-20170187062-A1 LITHIUM BATTERY ELECTROLYTE SOLUTION CONTAINING METHYL (2,2,3,3,-TETRAFLUOROPROPYL) CARBONATE DOW GLOBAL TECHNOLOGIES LLC 2017-06-29 US claimed
EP-4292708-B1 METHOD FOR PRODUCING CARBONYL HALIDE UNIV KOBE NAT UNIV CORP (JP) 2026-03-04 EP disclosed
EP-4292708-A1 METHOD FOR PRODUCING CARBONYL HALIDE National University Corporation Kobe University (JP) 2023-12-20 EP disclosed
US-20230348279-A1 METHOD FOR PRODUCING CARBONYL HALIDE NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2023-11-02 US disclosed
US-11695158-B2 Nonaqueous electrolyte, capacitor device using same, and carboxylic acid ester compound used in same MU IONIC SOLUTIONS CORPORATION (JP) 2023-07-04 US disclosed
WO-2023080052-A1 POLYURETHANE PRODUCTION METHOD 国立大学法人神戸大学 2023-05-11 WO disclosed
WO-2022172744-A1 METHOD FOR PRODUCING CARBONYL HALIDE 国立大学法人神戸大学 2022-08-18 WO disclosed
US-20210320334-A1 NONAQUEOUS ELECTROLYTE, CAPACITOR DEVICE USING SAME, AND CARBOXYLIC ACID ESTER COMPOUND USED IN SAME MU IONIC SOLUTIONS CORPORATION (JP) 2021-10-14 US disclosed
CN-110943253-A High-voltage lithium ion battery combined electrolyte additive, electrolyte and battery thereof 松山湖材料实验室 2020-03-31 CN disclosed
WO-2015183597-A1 LITHIUM BATTERY ELECTROLYTE SOLUTION CONTAINING ETHYL (2,2,3,3-TETRAFLUOROPROPYL) CARBONATE DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-03 WO disclosed
WO-2015183599-A1 LITHIUM BATTERY ELECTROLYTE SOLUTION CONTAINING METHYL (2,2,3,3,-TETRAFLUOROPROPYL) CARBONATE DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-03 WO disclosed
WO-2015183599-A1 LITHIUM BATTERY ELECTROLYTE SOLUTION CONTAINING METHYL (2,2,3,3,-TETRAFLUOROPROPYL) CARBONATE DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-03 WO disclosed
US-8735005-B2 Fluorinated cyclic carbonates and compositions thereof E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-27 US disclosed
US-8530099-B2 Multifunctional sulfone/fluorinated ester solvents E I DU PONT DE NEMOURS AND COMPANY (US) 2013-09-10 US disclosed
US-20120323036-A1 MULTIFUNCTIONAL SULFONE/FLUORINATED ESTER SOLVENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-12-20 US disclosed
US-20120141870-A1 MULTIFUNCTIONAL SULFONE/FLUORINATED ESTER SOLVENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-07 US disclosed
US-8092942-B1 Multifunctional sulfone/fluorinated ester solvents E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-10 US disclosed
US-20110244313-A1 Fluorinated Cyclic Carbonates and Compositions Thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11695158-B2 Nonaqueous electrolyte, capacitor device using same, and carboxylic acid ester compound used in same SLC9A2, VDAC1, SCO2 LMNA 4578/4885POLB 4477/4885TSHR 2418/4885
US-20120323036-A1 MULTIFUNCTIONAL SULFONE/FLUORINATED ESTER SOLVENTS PFAS, STS, SULT1E1 LMNA 3529/4885POLB 4351/4885TSHR 2217/4885
US-20210320334-A1 NONAQUEOUS ELECTROLYTE, CAPACITOR DEVICE USING SAME, AND CARBOXYLIC ACID ESTER COMPOUND USED IN SAME SLC9A2, VDAC1, SCO2 LMNA 4578/4885POLB 4477/4885TSHR 2418/4885
US-20120141870-A1 MULTIFUNCTIONAL SULFONE/FLUORINATED ESTER SOLVENTS PFAS, STS, SULT1E1 LMNA 3529/4885POLB 4351/4885TSHR 2217/4885
US-20110244313-A1 Fluorinated Cyclic Carbonates and Compositions Thereof CA2, PFAS, CA7 LMNA 1215/4885POLB 2704/4885TSHR 2987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.