SCHEMBL8939838

SCHEMBL8939838

C=CC(=C)C.C=CC(=C)C.C=Cc1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.43
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
NR4A1 P22736 1/20 0.40
MAOA P21397 1/20 0.39
ALDH1A1 P00352 2/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
TOP2A P11388 1/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8851232 1.00 RAB9A (0.50) RAB9ANPC1MEN1KMT2AATM
SCHEMBL8851333 1.00 RAB9A (0.50) RAB9ANPC1MEN1KMT2AATM
SCHEMBL9579178 0.92 RAB9A (0.54) RAB9ANPC1MEN1KMT2AATM
Styrene SCHEMBL27489496 0.92 ALDH1A1 (0.45) RAB9ANPC1MEN1KMT2AATM
Acrylonitrile SCHEMBL28869634 0.90 RAB9A (0.42) RAB9ANPC1MEN1KMT2AATM
Methyl Alcohol SCHEMBL28009509 0.90 RAB9A (0.61) RAB9ANPC1MEN1KMT2AATM
SCHEMBL27624568 0.87 NPC1 (0.48) RAB9ANPC1MEN1KMT2AATM
SCHEMBL9359592 0.85 MEN1 (0.67) RAB9ANPC1MEN1KMT2AATM
SCHEMBL29371456 0.85
SCHEMBL15193 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5550005-A BLOCK POLYMER W. R. GRACE & CO.-CONN. (US) 1996-08-27 US disclosed
US-5290662-A Quaternized triblock copolymers on backings W. R. GRACE & CO.-CONN. (US) 1994-03-01 US disclosed
US-5223375-A Butadiene-vinyl pyridine or isoprene-vinyl pyridene block polymer W. R. GRACE & CO.-CONN. (US) 1993-06-29 US disclosed