Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27641949 | 1.00 | ALOX12 (0.46) | ALOX12LMNATSHRACHEPTGS2 | |
| Benzene SCHEMBL2418654 | 0.91 | GABRA1 (0.48) | ALOX12TSHRPTGS2GABRA1GABRB2 | |
| O-Xylene SCHEMBL11099451 | 0.89 | TSHR (0.48) | ALOX12TSHRACHEPTGS2GABRA1 | |
| SCHEMBL29420847 | 0.89 | GABRA1 (0.50) | TSHRPTGS2GABRA1GABRB2NR3C1 | |
| SCHEMBL140570 | 0.89 | GABRA1 (0.50) | TSHRPTGS2GABRA1GABRB2NR3C1 | |
| Biphenyl SCHEMBL20493683 | 0.88 | PDCD1 (0.46) | ALOX12PTGS2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL10716892 | 0.87 | TAAR1 (0.45) | TSHRACHEPTGS2GABRA1GABRB2 | |
| Ammonia Solution, Strong SCHEMBL4439587 | 0.87 | GABRA1 (0.48) | TSHRPTGS2GABRA1GABRB2NR3C1 | |
| Water SCHEMBL27401389 | 0.87 | GABRA1 (0.48) | TSHRPTGS2GABRA1GABRB2NR3C1 | |
| SCHEMBL11666322 | 0.85 | GABRA1 (0.43) | ALOX12TSHRACHEPTGS2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699172-A1 | BIOREACTOR FOR BIOLOGICAL TREATMENT OF CONTAMINATED WATER | BIOREMETEK INC (CA) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994027919-A1 | BIOREACTOR FOR BIOLOGICAL TREATMENT OF CONTAMINATED WATER | BIOREMETEK INC. (CA) | 1994-12-08 | — | — | WO | disclosed |