Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18276239 | 0.88 | LMNA (0.37) | ALOX15BLMPMP22KMT2AGABRR1 | |
| SCHEMBL8940205 | 0.82 | TDP1 (0.48) | KMT2AGABRR1LMNACYP2C19TDP1 | |
| SCHEMBL28826882 | 0.78 | LMNA (0.35) | ALOX15BLMPMP22LMNACYP2C19 | |
| SCHEMBL10699308 | 0.78 | GRIK1 (0.37) | ALOX15BLMPMP22KMT2AGABRR1 | |
| SCHEMBL3978188 | 0.74 | — | — | |
| SCHEMBL7088106 | 0.74 | TDP1 (0.41) | LMNATDP1CA2ALDH1A1CA1 | |
| SCHEMBL23170133 | 0.73 | TDP1 (0.58) | ALOX15BLMPMP22KMT2AGABRR1 | |
| SCHEMBL14938352 | 0.73 | — | — | |
| SCHEMBL27538444 | 0.73 | SLC22A6 (0.45) | GABRR1LMNACYP2C19TDP1SMN1; SMN2 | |
| SCHEMBL16010192 | 0.72 | ECE1 (0.40) | ALOX15BLMPMP22KMT2AGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8176105-A | — | — | None | — | — | JP | disclosed |
| JP-H08176105-A | 2-CARBOXYSUCCINIC ACID IMIDE DERIVATIVE | DAINIPPON PHARMACEUT CO LTD | 1996-07-09 | — | — | JP | disclosed |
| EP-0066241-B1 | MODIFIED CIS-1,4-POLYISOPRENE RUBBER, A PROCESS FOR ITS MANUFACTURE, A VULCANIZED MODIFIED CIS-1,4-POLYISOPRENE RUBBER COMPOSITION AND THE USE OF THE MODIFIED CIS-1,4-POLYISOPRENE RUBBER FOR PREPARING VULCANIZED SHAPED ARTICLES | KURARAY CO., LTD. (JP) | 1985-05-08 | — | — | EP | disclosed |
| US-4446281-A | Modified cis-1,4-polyisoprene rubber, a process for manufacturing the same, and a composition containing the same | KURARAY CO., LTD. (JP) | 1984-05-01 | — | — | US | disclosed |
| EP-0066241-A2 | Modified cis-1,4-polyisoprene rubber, a process for its manufacture, a vulcanized modified cis-1,4-polyisoprene rubber composition and the use of the modified cis-1,4-polyisoprene rubber for preparing vulcanized shaped articles | KURARAY CO., LTD. (JP) | 1982-12-08 | — | — | EP | disclosed |