Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | CPB1 | P15086 | 2/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27538444 | 0.91 | SLC22A6 (0.45) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL8940204 | 0.82 | ALOX15 (0.39) | TDP1SMN1; SMN2GABRR1LMNACYP2C19 | |
| SCHEMBL110197 | 0.81 | TDP1 (0.59) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL5221301 | 0.78 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL8074653 | 0.78 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL1472841 | 0.78 | TDP1 (0.56) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL5681439 | 0.78 | TDP1 (0.56) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL5668507 | 0.76 | GABRP (0.37) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL8470668 | 0.76 | GABRP (0.37) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL3110310 | 0.75 | TDP1 (0.53) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296536-A1 | METHOD FOR PRODUCING DITHIINE TETRACARBOXIMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-02 | — | — | US | claimed |
| US-20140256956-A1 | METHOD FOR PRODUCING DITHINE TETRACARBOXIMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | claimed |
| CN-103874703-A | Method for preparing dithiine tetracarboxydiimides | BAYER IP GMBH | 2014-06-18 | — | — | CN | claimed |
| JP-8176105-A | — | — | None | — | — | JP | disclosed |
| CN-103649100-B | Platinum compound with leaving group of succinic acid derivative containing amino or alkylamino, preparation method and application thereof | 北京市丰硕维康技术开发有限责任公司 | 2016-06-22 | — | — | CN | disclosed |
| US-20140296536-A1 | METHOD FOR PRODUCING DITHIINE TETRACARBOXIMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140256956-A1 | METHOD FOR PRODUCING DITHINE TETRACARBOXIMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| CN-103874703-A | Method for preparing dithiine tetracarboxydiimides | BAYER IP GMBH | 2014-06-18 | — | — | CN | disclosed |
| CN-102993239-A | Platinum compound of succinic acid derivative with leaving group containing amino or alkylamino | CHEN XIAOPING | 2013-03-27 | — | — | CN | disclosed |
| JP-H08176105-A | 2-CARBOXYSUCCINIC ACID IMIDE DERIVATIVE | DAINIPPON PHARMACEUT CO LTD | 1996-07-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256956-A1 | METHOD FOR PRODUCING DITHINE TETRACARBOXIMIDES | TST, TXNDC5, TXN | TDP1 1497/4885SMN1; SMN2 3914/4885SLC22A6 4085/4885 |
| US-20140296536-A1 | METHOD FOR PRODUCING DITHIINE TETRACARBOXIMIDES | TST, TXNDC5, TMT1A | TDP1 1679/4885SMN1; SMN2 3842/4885SLC22A6 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.