Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159570 | 0.84 | MAPT (0.32) | MAPTGFER | |
| SCHEMBL4611388 | 0.80 | BRD4 (0.33) | MAPTGFER | |
| SCHEMBL8300720 | 0.76 | HTT (0.35) | — | |
| SCHEMBL8913135 | 0.76 | KMT2A (0.31) | — | |
| SCHEMBL6160228 | 0.75 | CYP1A2 (0.33) | — | |
| SCHEMBL8301187 | 0.74 | KDM4E (0.34) | MAPT | |
| SCHEMBL8301176 | 0.74 | HTT (0.36) | — | |
| SCHEMBL6158571 | 0.74 | PPIA (0.35) | MAPT | |
| SCHEMBL6159606 | 0.73 | OPRM1 (0.42) | — | |
| SCHEMBL8296784 | 0.73 | CA2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726893-A1 | NOVEL 4-PIPERIDINYL SUBSTITUTED LACTAMES AS NEUROKININ 2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ASTHMA | ZENECA LIMITED (GB) | 1996-08-21 | — | — | EP | disclosed |
| US-5534525-A | Lactam derivatives | ZENECA LIMITED (GB) | 1996-07-09 | — | — | US | disclosed |
| WO-1995012577-A1 | NOVEL 4-PIPERIDINYL SUBSTITUTED LACTAMES AS NEUROKININ 2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ASTHMA | ZENECA LIMITED (GB) | 1995-05-11 | — | — | WO | disclosed |