Cyclohexylamine

Cyclohexylamine

SCHEMBL8940507

NC1CCCCC1.O=C(OC(=O)c1ccccc1)c1ccccc1.[NaH]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 1/20 0.44
SCN1A P35498 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN3A Q9NY46 1/20 0.44
KMT2A Q03164 4/20 0.44
MEN1 O00255 2/20 0.44
ATM Q13315 1/20 0.44
F2 P00734 1/20 0.44
POLB P06746 2/20 0.42
ELANE P08246 1/20 0.42
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 2/20 0.41
CHRNA7 P36544 2/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL975787 0.89 LMNA (0.42) LMNACYP1A2CYP2D6SCN1ASCN2A
Cyclohexane SCHEMBL28376326 0.83 LMNA (0.61) LMNAKMT2AMEN1F2POLB
Benzoic Acid SCHEMBL28845890 0.82 DAO (0.52) KMT2APOLBELANECHRM2CHRM1
Benzophenone SCHEMBL11575706 0.82 ALDH1A1 (0.56) LMNAKMT2AMEN1ATMPOLB
Benzoic Acid SCHEMBL597061 0.82 TSHR (0.56) KMT2APOLBELANECHRM2CHRM1
SCHEMBL27506995 0.81 LMNA (0.49) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL431406 0.79 LMNA (0.67) LMNAKMT2AF2POLBTSHR
SCHEMBL2591454 0.79 LMNA (0.67) LMNAKMT2AF2POLBTSHR
Cyclohexylamine SCHEMBL10638255 0.78 CYP2D6 (0.40) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL5788955 0.77 ELANE (0.58) LMNACYP1A2CYP2D6SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707666-A4 CORROSION INHIBITOR AND SEALABLE THREAD PROTECTOR END CAP CENTRAX INT CORP (US) 1996-10-09 EP disclosed
EP-0707666-A1 CORROSION INHIBITOR AND SEALABLE THREAD PROTECTOR END CAP CENTRAX INTERNATIONAL CORPORATION (US) 1996-04-24 EP disclosed
WO-1995000679-A1 CORROSION INHIBITOR AND SEALABLE THREAD PROTECTOR END CAP CENTRAX INTERNATIONAL CORPORATION (US) 1995-01-05 WO disclosed