Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160862 | 0.78 | OPRL1 (0.50) | DRD2CYP2D6ALDH1A1TSHRCYP2C19 | |
| SCHEMBL1269458 | 0.76 | CYP2D6 (0.61) | DRD2DRD4DRD3CYP2D6ALDH1A1 | |
| SCHEMBL14716240 | 0.74 | CYP2D6 (0.63) | DRD2DRD4DRD3CYP2D6ALDH1A1 | |
| SCHEMBL4828466 | 0.73 | OPRL1 (0.48) | DRD2CYP2D6ALDH1A1TSHRCYP2C19 | |
| SCHEMBL14081425 | 0.71 | CYP2D6 (0.56) | DRD2DRD4DRD3CYP2D6ALDH1A1 | |
| SCHEMBL15505949 | 0.71 | HDAC1 (0.58) | DRD2DRD4DRD3CYP2D6ALDH1A1 | |
| SCHEMBL653329 | 0.71 | OPRL1 (0.67) | CYP2D6ALDH1A1TSHRCYP2C19KMT2A | |
| SCHEMBL4293243 | 0.71 | DRD2 (0.55) | DRD2DRD4DRD3CYP2D6ALDH1A1 | |
| SCHEMBL17608847 | 0.70 | LTA4H (0.62) | DRD2CYP2D6ALDH1A1TSHRCYP2C19 | |
| SCHEMBL2086353 | 0.69 | MEN1 (0.51) | DRD2CYP2D6ALDH1A1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534525-A | Lactam derivatives | ZENECA LIMITED (GB) | 1996-07-09 | — | — | US | disclosed |