Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940653 | 0.87 | ALDH1A1 (0.49) | L3MBTL1APPKDM4EALDH1A1MAPT | |
| SCHEMBL25797846 | 0.83 | APP (0.46) | APPPDK2 | |
| SCHEMBL25797920 | 0.83 | APP (0.46) | APPPDK2 | |
| SCHEMBL25797612 | 0.83 | NR5A1 (0.51) | PDK2LTA4HTSHR | |
| SCHEMBL2097133 | 0.82 | APP (0.49) | L3MBTL1APPMAPTMEN1KMT2A | |
| SCHEMBL8386278 | 0.82 | ALDH1A1 (0.58) | L3MBTL1KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL7687597 | 0.81 | ALDH1A1 (0.47) | APPKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL29956388 | 0.81 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL6495895 | 0.79 | BCHE (0.54) | KDM4EALDH1A1MAPTHSD17B10NQO1 | |
| SCHEMBL25797659 | 0.78 | PDK2 (0.46) | APPPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |