Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.73 |
| ▸ | CNR2 | P34972 | 1/20 | 0.73 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.69 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940800 | 0.90 | GABRA1 (0.60) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL10054534 | 0.90 | CNR1 (0.59) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL15055469 | 0.89 | GABRA1 (0.58) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL8940890 | 0.88 | GABRA1 (0.57) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL662610 | 0.86 | CNR1 (1.00) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL29380189 | 0.86 | CNR1 (1.00) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL267532 | 0.82 | TAAR1 (0.73) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL29833121 | 0.82 | CYP3A4 (0.71) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL901444 | 0.82 | CYP3A4 (0.71) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL9679818 | 0.81 | GABRA1 (0.57) | GABRA1GABRB2ALOX5TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| EP-0581777-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992017449-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1992-10-15 | — | — | WO | disclosed |