Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.49 |
| ▸ | FOS | P01100 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940661 | 0.90 | CNR1 (0.73) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL8940800 | 0.81 | GABRA1 (0.60) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL15055469 | 0.81 | GABRA1 (0.58) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL8940890 | 0.79 | GABRA1 (0.57) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL13818321 | 0.79 | GABRA1 (0.68) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL15004288 | 0.79 | GABRA1 (0.51) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL29380189 | 0.77 | CNR1 (1.00) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL662610 | 0.77 | CNR1 (1.00) | CNR1CNR2GABRA1GABRB2ALOX5 | |
| SCHEMBL20821072 | 0.76 | ALOX15 (0.80) | GABRA1GABRB2ALOX15ALOX12FOS | |
| SCHEMBL11571527 | 0.76 | FOS (0.80) | GABRA1GABRB2ALOX5ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083008-A1 | Methods for obtaining molecules with reduced immunogenicity | MARSHALL CHRISTOPHER P (US) | 2012-04-05 | — | — | US | disclosed |