SCHEMBL8940846

SCHEMBL8940846

CN(CCO)CCNCCO

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.33
PAOX Q6QHF9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethanolamine SCHEMBL27473413 0.95 MAPT (0.43) MAPTCYP2C9CYP2C19TDP1PAOX
SCHEMBL9597791 0.88 TDP1 (0.41) MAPTCYP2C9CYP2C19TDP1PAOX
SCHEMBL25792055 0.86 CYP2C9 (0.33) MAPTCYP2C9CYP2C19TDP1
SCHEMBL4083018 0.86 PRMT3 (0.44) MAPTCYP2C9CYP2C19TDP1
SCHEMBL5616281 0.83 MAPT (0.38) MAPTCYP2C9CYP2C19
SCHEMBL13752280 0.83 CYP2C9 (0.34) MAPTCYP2C9CYP2C19TDP1PAOX
SCHEMBL9216980 0.82 CYP2C19 (0.56) MAPTCYP2C9CYP2C19TDP1PAOX
SCHEMBL5911036 0.82 TDP1 (0.44) MAPTCYP2C9CYP2C19TDP1PAOX
SCHEMBL3378610 0.80 TDP1 (0.43) MAPTCYP2C9CYP2C19TDP1PAOX
SCHEMBL16730591 0.80 TDP1 (0.43) MAPTCYP2C9CYP2C19TDP1PAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5491263-A DECYCLIZATION OF AN OXAZOLIDINONE WITH A SECONDARY AMINE OR A SECONDARY ALKANOLAMINE THE DOW CHEMICAL COMPANY (US) 1996-02-13 US disclosed
US-4739042-A ESTERIFICATION OF AN HYDROXY PYRIDONE DYESTUFF WITH CARBOXYLIC PYRIDINE DYESTUFF BAYER AKTIENGESELLSCHAFT (DE) 1988-04-19 US disclosed