Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28161630 | 0.87 | GAA (0.67) | ALDH1A1ALOX15USP2GAAPKM | |
| SCHEMBL178482 | 0.85 | TSHR (0.62) | ALDH1A1ALOX15USP2GAAPKM | |
| SCHEMBL2740733 | 0.83 | TUBB4A (0.57) | ALDH1A1ALOX15USP2GAAPKM | |
| SCHEMBL8298141 | 0.79 | ALDH1A1 (0.60) | ALDH1A1ALOX15USP2GAAPKM | |
| SCHEMBL12909064 | 0.76 | ALDH1A1 (0.47) | ALDH1A1ALOX15USP2GAAPKM | |
| SCHEMBL9963706 | 0.75 | ALDH1A1 (0.49) | ALDH1A1ALOX15USP2GAAPKM | |
| SCHEMBL11436456 | 0.74 | ALDH1A1 (0.49) | ALDH1A1ALOX15USP2GAAPKM | |
| SCHEMBL18885070 | 0.74 | TSHR (0.57) | TSHRCYP3A4NFKB1BCHETYR | |
| SCHEMBL4976111 | 0.74 | ALDH1A1 (0.49) | ALDH1A1ALOX15USP2GAAPKM | |
| SCHEMBL17070149 | 0.74 | ALDH1A1 (0.56) | ALDH1A1ALOX15USP2GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |