SCHEMBL8940892

SCHEMBL8940892

CCn1ncc(C(=O)c2cc(F)c3c(c2C)C(OC)CC(C)S3)c1O

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8307884 0.94 ALDH1A1 (0.31) RAB9ASMN1; SMN2ALDH1A1CYP1A2CYP2C19
SCHEMBL8308933 0.82
SCHEMBL8941027 0.77 PDE4B (0.30)
SCHEMBL8940911 0.77 RAB9A (0.31) RAB9ASMN1; SMN2ALDH1A1CYP1A2CYP2C19
SCHEMBL8303171 0.77
SCHEMBL8303234 0.75
SCHEMBL8892726 0.73 ALDH1A1 (0.35) RAB9ASMN1; SMN2ALDH1A1CYP1A2CYP2C19
SCHEMBL8940874 0.73 RAB9A (0.31) RAB9ASMN1; SMN2ALDH1A1CYP1A2CYP2C19
SCHEMBL8135089 0.71 RAB9A (0.34) RAB9ASMN1; SMN2ALDH1A1CYP1A2CYP2C19
SCHEMBL8941039 0.71 PDE4B (0.32) RAB9ASMN1; SMN2ALDH1A1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5587484-A HALOGENATION; OXIDATION; SULFONATION; HERBICIDES IDEMITSU KOSAN CO., LTD. (JP) 1996-12-24 US disclosed