Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708046 | 0.88 | MAPT (0.52) | ESR1ESR2ALDH1A1HPGDMAPT | |
| SCHEMBL29786696 | 0.88 | MAPT (0.52) | ESR1ESR2ALDH1A1HPGDMAPT | |
| SCHEMBL12408907 | 0.84 | HDAC6 (0.45) | ESR1ESR2ALDH1A1HPGDMAPT | |
| SCHEMBL29819736 | 0.83 | HDAC6 (0.55) | ESR1ESR2ALDH1A1HPGDMAPT | |
| SCHEMBL28831124 | 0.83 | HDAC6 (0.55) | ESR1ESR2ALDH1A1HPGDMAPT | |
| SCHEMBL14000535 | 0.81 | HDAC6 (0.63) | ESR1ESR2ALDH1A1HPGDMAPT | |
| SCHEMBL14666781 | 0.81 | KDM4E (0.54) | ALDH1A1HPGDMAPTKDM4EUSP2 | |
| SCHEMBL28618111 | 0.80 | MAPT (0.65) | ESR1ESR2ALDH1A1HPGDMAPT | |
| SCHEMBL12304267 | 0.80 | HSD17B10 (0.66) | ESR1ESR2ALDH1A1HPGDMAPT | |
| SCHEMBL8940990 | 0.79 | MAPT (0.44) | ESR1ESR2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518656-A | BIS/ALKYLBENZOXAZOLYL/NAPHTHALENE OR 1,5-DIPHENYL-3-STYRYLPYRAZOLINE | NIPPON CHEMICAL WORKS CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |