Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708051 | 0.96 | MAPT (0.47) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL29786696 | 0.90 | MAPT (0.52) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5708046 | 0.90 | MAPT (0.52) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL8940994 | 0.84 | CNR1 (0.43) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL28618111 | 0.82 | MAPT (0.65) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL15257105 | 0.80 | ALDH1A1 (0.42) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5708053 | 0.80 | CNR1 (0.46) | MAPTALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL8940957 | 0.79 | ESR1 (0.56) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5708121 | 0.77 | F2RL3 (0.44) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL10256180 | 0.77 | MAPT (0.66) | MAPTNPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518656-A | BIS/ALKYLBENZOXAZOLYL/NAPHTHALENE OR 1,5-DIPHENYL-3-STYRYLPYRAZOLINE | NIPPON CHEMICAL WORKS CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |