Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 5/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941117 | 0.99 | MGLL (0.36) | GRIN1GRIN2BMGLLNAAAFPR2 | |
| SCHEMBL18718300 | 0.96 | FPR2 (0.35) | GRIN1GRIN2BMGLLFPR2SLC6A2 | |
| SCHEMBL18718305 | 0.95 | MGLL (0.37) | GRIN1GRIN2BMGLLFPR2SLC6A2 | |
| SCHEMBL18718313 | 0.95 | MGLL (0.37) | GRIN1GRIN2BMGLLFPR2SLC6A2 | |
| SCHEMBL8932646 | 0.94 | GRIN1 (0.33) | GRIN1GRIN2BNAAAFPR2 | |
| SCHEMBL18718284 | 0.93 | FPR2 (0.36) | GRIN1GRIN2BMGLLFPR2SLC6A2 | |
| SCHEMBL8940704 | 0.93 | GRIN1 (0.36) | GRIN1GRIN2BNAAAFPR2SLC6A2 | |
| SCHEMBL8941060 | 0.93 | GRIN1 (0.33) | GRIN1GRIN2BMGLLNAAAFPR2 | |
| SCHEMBL8941011 | 0.92 | PTPN11 (0.33) | GRIN1GRIN2BFPR2 | |
| SCHEMBL8941033 | 0.92 | S1PR1 (0.33) | GRIN1GRIN2BFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |