Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.56 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941124 | 1.00 | TBXAS1 (0.56) | TBXAS1CES2CES1TDP1SOAT2 | |
| Ethylene Glycol SCHEMBL7783597 | 0.88 | TBXAS1 (0.59) | TBXAS1CES2CES1TDP1SOAT2 | |
| SCHEMBL16167100 | 0.79 | TBXAS1 (0.46) | TBXAS1CES2CES1SOAT2SOAT1 | |
| SCHEMBL28481686 | 0.78 | TBXAS1 (0.48) | TBXAS1CES2CES1SOAT2SOAT1 | |
| SCHEMBL299556 | 0.78 | CES2 (0.50) | TBXAS1CES2CES1TDP1LMNA | |
| SCHEMBL9312401 | 0.77 | CES2 (0.56) | TBXAS1CES2CES1TDP1EPHX2 | |
| SCHEMBL27526812 | 0.77 | CES2 (0.56) | TBXAS1CES2CES1TDP1EPHX2 | |
| SCHEMBL27608811 | 0.77 | CES2 (0.56) | TBXAS1CES2CES1TDP1EPHX2 | |
| SCHEMBL11896276 | 0.77 | CES2 (0.56) | TBXAS1CES2CES1TDP1EPHX2 | |
| SCHEMBL28481685 | 0.77 | TBXAS1 (0.47) | TBXAS1CES2CES1TDP1SOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | disclosed |