Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599568 | 0.84 | AKR1C3 (0.46) | CYP1A2CYP2A6AKR1C3AKR1C2AKR1B1 | |
| SCHEMBL13626145 | 0.82 | MTNR1A (0.52) | CYP1A2AKR1C3AKR1C2PTGS1MAPT | |
| SCHEMBL10350347 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1TP53ALDH1A1 | |
| SCHEMBL9857537 | 0.79 | CNR2 (0.48) | CYP1A2CYP2A6TP53ALDH1A1MEN1 | |
| SCHEMBL22389564 | 0.76 | PTGS2 (0.55) | PTGS2AKR1C3PTGS1TP53ALDH1A1 | |
| SCHEMBL13626838 | 0.74 | MTNR1A (0.53) | CYP1A2MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL27326726 | 0.74 | CNR1 (0.44) | CYP1A2CYP2A6MAPTKDM4EALDH1A1 | |
| SCHEMBL28096196 | 0.74 | CYP1A2 (0.50) | CYP1A2CYP2A6AKR1C3AKR1C2AKR1B1 | |
| SCHEMBL11233529 | 0.73 | TP53 (0.47) | CYP1A2PTGS2AKR1C3PTGS1TP53 | |
| SCHEMBL3949360 | 0.73 | CYP1A2 (0.47) | CYP1A2CYP2A6AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713501-A1 | NAPHTHALENEDICARBOXYLIC ACID CONTAINING POLYMER COMPOSITIONS HAVING REDUCED FLUORESCENCE | EASTMAN CHEM CO (US) | 1996-05-29 | — | — | EP | disclosed |
| WO-1995004768-A1 | NAPHTHALENEDICARBOXYLIC ACID CONTAINING POLYMER COMPOSITIONS HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 1995-02-16 | — | — | WO | disclosed |