Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380470 | 0.84 | TSHR (0.50) | KDM4EHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8381827 | 0.80 | KDM4E (0.54) | KDM4EHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8378478 | 0.77 | TSHR (0.51) | KDM4EHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8378602 | 0.76 | TSHR (0.50) | KDM4EHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8382975 | 0.72 | KDM4E (0.54) | KDM4ECYP2C8CYP2C9HSD17B10TSHR | |
| SCHEMBL8380474 | 0.72 | TSHR (0.51) | KDM4EHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL235942 | 0.71 | MAPT (0.59) | KDM4EHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL236293 | 0.71 | TSHR (0.50) | KDM4EHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8674887 | 0.71 | TSHR (0.53) | KDM4EHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5965482 | 0.70 | AKR1C3 (0.51) | KDM4EHPGDCYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713506-A1 | A PROCESS FOR PREPARING NAPHTHALENEDICARBOXYLIC ACID CONTAINING POLYMER BLENDS HAVING REDUCED FLUORESCENCE | EASTMAN CHEM CO (US) | 1996-05-29 | — | — | EP | disclosed |
| WO-1995004777-A1 | A PROCESS FOR PREPARING NAPHTHALENEDICARBOXYLIC ACID CONTAINING POLYMER BLENDS HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 1995-02-16 | — | — | WO | disclosed |