Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15801005 | 0.81 | KMT2A (0.52) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL15765777 | 0.78 | KDM4E (0.47) | PPARGPPARAALDH1A1MRGPRX4KDM4E | |
| SCHEMBL15454071 | 0.77 | L3MBTL1 (0.49) | PPARGPPARAALDH1A1KMT2AMEN1 | |
| SCHEMBL15765735 | 0.75 | KDM4E (0.57) | PPARGPPARAKMT2ALMNAMEN1 | |
| SCHEMBL6938268 | 0.75 | NR3C1 (0.48) | PPARGPPARAALDH1A1LMNAMAPT | |
| SCHEMBL28327548 | 0.75 | KDM4E (0.54) | PPARGPPARAALDH1A1KMT2ALMNA | |
| SCHEMBL8941232 | 0.74 | NR3C1 (0.47) | PPARGPPARAALDH1A1KMT2ALMNA | |
| SCHEMBL15763979 | 0.74 | SMN1; SMN2 (0.44) | PPARGPPARAALDH1A1KMT2ALMNA | |
| SCHEMBL17358637 | 0.74 | KDM4E (0.48) | PPARGPPARAALDH1A1MAPTMRGPRX4 | |
| SCHEMBL27801587 | 0.73 | L3MBTL1 (0.46) | PPARGPPARAALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |