Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.48 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941313 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2ATDP1SOAT1 | |
| SCHEMBL8941381 | 0.91 | SOAT1 (0.55) | SMN1; SMN2MEN1KMT2ATDP1SOAT1 | |
| SCHEMBL9359202 | 0.82 | NLRP3 (0.56) | SMN1; SMN2 | |
| SCHEMBL8941146 | 0.81 | SOAT2 (0.47) | SOAT1SOAT2MYCMAP2K3 | |
| SCHEMBL8941512 | 0.80 | SOAT2 (0.46) | SOAT1SOAT2MYCMAP2K3 | |
| SCHEMBL8941187 | 0.79 | TSHR (0.48) | SOAT1SOAT2MYCMAP2K3 | |
| SCHEMBL8962535 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2MEN1KMT2ATDP1SOAT1 | |
| SCHEMBL8941439 | 0.77 | — | — | |
| SCHEMBL8041519 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2ATDP1SOAT1 | |
| SCHEMBL9843936 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2MEN1KMT2ATDP1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | claimed |
| WO-1996019444-A1 | SULFONATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5510379-A | USEFUL FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |