SCHEMBL8941507

SCHEMBL8941507

Fc1ccc(Oc2cccc(F)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HTT P42858 1/20 0.50
F2 P00734 1/20 0.44
F10 P00742 1/20 0.44
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
ST14 Q9Y5Y6 1/20 0.44
KDM4E B2RXH2 1/20 0.44
P2RX3 P56373 2/20 0.42
CHRM5 P08912 1/20 0.41
ALDH1A1 P00352 1/20 0.41
FPR2 P25090 1/20 0.40
SCN9A Q15858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8941674 0.86 F2 (0.46) HTTF2F10PRSS1PRSS2
SCHEMBL9268808 0.85 MEN1 (0.47) MEN1KMT2AL3MBTL1HTTF2
SCHEMBL21330627 0.85 MEN1 (0.52) MEN1KMT2AHTTF2F10
SCHEMBL21330612 0.85 MEN1 (0.51) MEN1KMT2AL3MBTL1HTTP2RX3
SCHEMBL21330640 0.85 MEN1 (0.48) MEN1KMT2AL3MBTL1HTTKDM4E
SCHEMBL11684536 0.85 MEN1 (0.47) MEN1KMT2AF2F10PRSS1
SCHEMBL22061575 0.83 F2 (0.41) F2F10PRSS1PRSS2PRSS3
SCHEMBL7228289 0.82 KDM4E (0.47) F2F10PRSS1PRSS2PRSS3
SCHEMBL16695498 0.81 MEN1 (0.51) MEN1KMT2AL3MBTL1HTTF2
SCHEMBL5346192 0.81 MEN1 (0.50) MEN1KMT2AL3MBTL1HTTF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480568-A FOR LUBRICATING METAL CONTAINING SURFACES THE DOW CHEMICAL COMPANY (US) 1996-01-02 US disclosed