Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21330640 | 0.85 | MEN1 (0.48) | MEN1KMT2ANPC1ALDH1A1HTT | |
| SCHEMBL8941507 | 0.85 | MEN1 (0.50) | MEN1KMT2AALDH1A1HTTP2RX3 | |
| SCHEMBL8941674 | 0.82 | F2 (0.46) | NPC1ALDH1A1HTTRAB9AMAP4K4 | |
| SCHEMBL21330612 | 0.81 | MEN1 (0.51) | MEN1KMT2AHTTP2RX3 | |
| SCHEMBL11684536 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1F2F10 | |
| SCHEMBL10546373 | 0.81 | MEN1 (0.55) | MEN1KMT2ANPC1ALDH1A1HPGD | |
| SCHEMBL9986917 | 0.81 | F2 (0.39) | MEN1KMT2AHTTP2RX3F2 | |
| SCHEMBL22061575 | 0.80 | F2 (0.41) | MAP4K4F2F10PRSS1PRSS2 | |
| SCHEMBL7228289 | 0.79 | KDM4E (0.47) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8941703 | 0.78 | MEN1 (0.46) | MEN1KMT2AP2RX3FPR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265607-A1 | AMINOPYRIDINE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2023-10-25 | — | — | EP | disclosed |
| US-11739090-B2 | Substituted pyrazlo[3,4-c]pyridines as selective BTK kinase inhibitors | JUMBO DRUG BANK CO., LTD. (CN) | 2023-08-29 | — | — | US | disclosed |
| US-10711006-B2 | Selective Bruton's tyrosine kinase inhibitor and use thereof | HANGZHOU HERTZ PHARMACEUTICAL CO., LTD. (CN) | 2020-07-14 | — | — | US | disclosed |
| CN-108069974-B | Selective Bruton tyrosine kinase inhibitor and application thereof | HANGZHOU HERTZ PHARMACEUTICAL CO., LTD. (CN) | 2019-12-10 | — | — | CN | disclosed |
| EP-3543239-A1 | SELECTIVE BRUTON'S TYROSINE KINASE INHIBITOR AND USE THEREOF | Hangzhou Hertz Pharmaceutical Co., Ltd. (CN) | 2019-09-25 | — | — | EP | disclosed |
| US-20190276461-A1 | SELECTIVE BRUTON'S TYROSINE KINASE INHIBITOR AND USE THEREOF | Hangzhou Healzen Therapeutics Co., Ltd. (CN) | 2019-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276461-A1 | SELECTIVE BRUTON'S TYROSINE KINASE INHIBITOR AND USE THEREOF | BTK, BMX, KCNK10 | MEN1 2111/4885KMT2A 2028/4885NPC1 3441/4885 |
| US-10711006-B2 | Selective Bruton's tyrosine kinase inhibitor and use thereof | BTK, SYK, LYN | MEN1 2441/4885KMT2A 1652/4885NPC1 3687/4885 |
| US-11739090-B2 | Substituted pyrazlo[3,4-c]pyridines as selective BTK kinase inhibitors | BTK, SYK, LCK | MEN1 3580/4885KMT2A 1568/4885NPC1 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.