SCHEMBL8941525

SCHEMBL8941525

NC(CSSC[C@H](N)C(=O)OCC(O)CO)C(=O)OCC(O)CO

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
KDM4E B2RXH2 1/20 0.40
DUSP3 P51452 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
DGKA P23743 1/20 0.34
FAAH O00519 2/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5712805 0.85 LMNA (0.43) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL8630034 0.80 PTGS1 (0.41) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL592069 0.80 PTGS1 (0.41) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL15392088 0.80 LMNA (0.47) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL788418 0.80 PTGS1 (0.41) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL1824408 0.78 KDM4E (0.39) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL28300423 0.78 KDM4E (0.46) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL28101317 0.78 SLC22A6 (0.39) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL28285782 0.77 SLC7A5 (0.45) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL20489390 0.76 GRM8 (0.48) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5503826-A Hair keratin-reducing mono, di- and triglycerides of cysteine and compositions WELLA AKTIENGESELLSCHAFT (DE) 1996-04-02 US disclosed