SCHEMBL8941550

SCHEMBL8941550

CS(=O)(=O)c1ccc(Oc2ccc(C(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.59
PTGS2 P35354 3/20 0.56
ELANE P08246 1/20 0.54
STS P08842 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6583952 0.89 PTGS2 (0.65) PTGS2
SCHEMBL17296974 0.85 PARP10 (0.54) SRD5A2PTGS2STS
SCHEMBL7359540 0.84 SOS1 (0.64) PTGS2
SCHEMBL28938440 0.84 SRD5A2 (0.80) SRD5A2ELANESTSPOLB
SCHEMBL124917 0.84 SRD5A2 (0.80) SRD5A2ELANESTSPOLB
SCHEMBL9809047 0.84 SRD5A2 (0.80) SRD5A2ELANESTSPOLB
SCHEMBL9419497 0.84 SRD5A2 (0.80) SRD5A2ELANESTSPOLB
SCHEMBL23126855 0.83 STS (0.61) SRD5A2PTGS2STS
SCHEMBL10834156 0.83 ADAMTS4 (0.50) SRD5A2PTGS2ELANESTSPOLB
SCHEMBL234249 0.82 SRD5A2 (0.84) SRD5A2ELANESTSPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480568-A FOR LUBRICATING METAL CONTAINING SURFACES THE DOW CHEMICAL COMPANY (US) 1996-01-02 US claimed
US-4349568-A Sulfur-substituted diphenyl ethers having antiviral activity THE DOW CHEMICAL COMPANY (US) 1982-09-14 US claimed
US-5480568-A FOR LUBRICATING METAL CONTAINING SURFACES THE DOW CHEMICAL COMPANY (US) 1996-01-02 US disclosed
US-4505929-A Sulfur-substituted diphenyl ethers having antiviral activity THE DOW CHEMICAL COMPANY (US) 1985-03-19 US disclosed
US-4349568-A Sulfur-substituted diphenyl ethers having antiviral activity THE DOW CHEMICAL COMPANY (US) 1982-09-14 US disclosed