Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941636 | 0.80 | HTT (0.44) | PTPN1EPAS1PTGS1PTGS2HTT | |
| SCHEMBL9778980 | 0.75 | CA1 (0.45) | EPAS1CA1CA2CA9CASP1 | |
| SCHEMBL8941637 | 0.74 | PTPRZ1 (0.49) | PTPN1EPAS1HTTALDH1A1MAPK1 | |
| SCHEMBL8855056 | 0.73 | CA1 (0.46) | EPAS1CA1CA2CA9CASP1 | |
| SCHEMBL8941549 | 0.71 | SOS1 (0.49) | CA1CA2CA9HTTALDH1A1 | |
| SCHEMBL3870764 | 0.71 | CA1 (0.44) | EPAS1CA1CA2CA9CASP1 | |
| SCHEMBL6820329 | 0.71 | CA1 (0.51) | CA1CA2CA9CA12L3MBTL1 | |
| SCHEMBL7998942 | 0.71 | SLC6A4 (0.51) | PTGS2HTTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9242715 | 0.70 | CASP1 (0.49) | CA1CA2CA9CASP1HTT | |
| SCHEMBL5919462 | 0.70 | CASP1 (0.43) | CA1CA2CA9CASP1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |