Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.42 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.42 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.56 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | RAD52 | P43351 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17911670 | 1.00 | KDM4A (0.56) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4370196 | 0.98 | KDM4A (0.57) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL19582767 | 0.98 | KDM4A (0.57) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL19582692 | 0.98 | KDM4A (0.57) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL19582519 | 0.98 | KDM4A (0.57) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29431056 | 0.98 | KDM4A (0.57) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A | |
| Bromide SCHEMBL2425549 | 0.97 | KDM4A (0.56) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A | |
| Iodide SCHEMBL10938526 | 0.97 | KDM4A (0.58) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A | |
| Iodide SCHEMBL10938556 | 0.97 | KDM4A (0.58) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A | |
| Bromide SCHEMBL28803406 | 0.97 | KDM4A (0.56) | KDM4AKDM2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5529877-A | Microcapsule toner and processes for preparation of microcapsule and microcapsule toner | FUJI XEROX CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| US-5385802-A | Process for producing toner | FUJI XEROX CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |
| US-5336582-A | Electrophotographic image formation comprising an arylamine in a charge transport layer and an encapsulated toner | FUJI XEROX CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |