Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
| ▸ | ATP4B | P51164 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331974 | 1.00 | SLC2A1 (0.47) | SLC2A1MEN1KMT2AATMCYP2C9 | |
| SCHEMBL11736830 | 0.89 | SLC2A1 (0.57) | SLC2A1MEN1KMT2AATMCYP2C9 | |
| SCHEMBL13486908 | 0.86 | MEN1 (0.49) | SLC2A1MEN1KMT2AATMCYP2C9 | |
| SCHEMBL11673960 | 0.85 | ALOX5 (0.54) | SLC2A1MEN1KMT2AATMCYP2C9 | |
| SCHEMBL12405304 | 0.83 | MEN1 (0.47) | SLC2A1MEN1KMT2AATMCYP2C9 | |
| SCHEMBL11315591 | 0.82 | TDP1 (0.42) | CYP2C9 | |
| SCHEMBL9122622 | 0.81 | TAAR1 (0.67) | HTR1AADRA1DADRA1AADRA1BTAAR1 | |
| SCHEMBL31332014 | 0.81 | TAAR1 (0.67) | HTR1AADRA1DADRA1AADRA1BTAAR1 | |
| SCHEMBL8941972 | 0.81 | HTR1A (0.45) | SLC2A1MEN1KMT2AATMCYP2C9 | |
| SCHEMBL29474956 | 0.80 | TAAR1 (0.64) | SIGMAR1TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480913-A | DIHYDRO-PHENANTHRENE DERIVATIVES, SIDE EFFECT REDUCTION | ARCH DEVELOPMENT CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0363128-B1 | ANTI-ANDROGEN COMPOUNDS | ARCH DEVELOPMENT CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5208263-A | Dihydrophenanthrene derivatives | ARCH DEVELOPMENT CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |
| WO-1990003979-A2 | ANTI-ANDROGEN COMPOUNDS | ARCH DEVELOPMENT CORPORATION (US) | 1990-04-19 | — | — | WO | disclosed |
| EP-0363128-A2 | Anti-androgen compounds | ARCH DEVELOPMENT CORPORATION (US) | 1990-04-11 | — | — | EP | disclosed |