Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941940 | 0.91 | ALDH1A1 (0.39) | TOP1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8942035 | 0.91 | TOP1 (0.38) | TOP1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8942041 | 0.91 | TOP1 (0.42) | TOP1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8942032 | 0.89 | DRD3 (0.41) | TOP1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8942236 | 0.89 | TOP1 (0.39) | TOP1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8941913 | 0.89 | LMNA (0.51) | TOP1LMNACYP2C9ATP6V1B2TBXA2R | |
| Water SCHEMBL8942061 | 0.89 | DRD3 (0.40) | TOP1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8942031 | 0.87 | KMT2A (0.46) | TOP1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8942103 | 0.87 | LMNA (0.38) | TOP1LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8942126 | 0.87 | KDM4E (0.49) | TOP1LMNACYP2C9KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |