Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942032 | 0.90 | DRD3 (0.41) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8942041 | 0.90 | TOP1 (0.42) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| Water SCHEMBL8942061 | 0.89 | DRD3 (0.40) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8942224 | 0.89 | ALDH1A1 (0.48) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8941960 | 0.89 | DPP4 (0.49) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8942000 | 0.88 | KMT2A (0.48) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8942003 | 0.88 | ALDH1A1 (0.40) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8941931 | 0.88 | ALDH1A1 (0.38) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8942082 | 0.88 | TOP1 (0.41) | TOP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8942065 | 0.88 | TOP1 (0.41) | TOP1ALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |