SCHEMBL8942

SCHEMBL8942

CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 4/20 1.00
AR P10275 3/20 1.00
CHRM1 P11229 2/20 1.00
LMNA P02545 6/20 0.70
NR3C1 P04150 5/20 0.70
HIF1A Q16665 5/20 0.70
CYP3A4 P08684 5/20 0.70
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
SMN1; SMN2 Q16637 4/20 0.70
CYP2C9 P11712 4/20 0.70
NPSR1 Q6W5P4 2/20 0.70
MAPK1 P28482 2/20 0.70
ABCB11 O95342 1/20 0.70
POLB P06746 1/20 0.70
CYP19A1 P11511 3/20 0.63
TDP1 Q9NUW8 1/20 0.63
CYP2C19 P33261 4/20 0.59
MAPT P10636 2/20 0.59
ADORA3 P0DMS8 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2294866 1.00 PGR (1.00) PGRARCHRM1LMNANR3C1
SCHEMBL5020044 1.00 PGR (1.00) PGRARCHRM1LMNANR3C1
SCHEMBL16690685 1.00 PGR (1.00) PGRARCHRM1LMNANR3C1
Acetic Acid SCHEMBL25192781 0.98 PGR (0.96) PGRARCHRM1LMNANR3C1
Acetic Acid SCHEMBL28104035 0.97 PGR (0.94) PGRARCHRM1LMNANR3C1
Ethylene Glycol SCHEMBL28094936 0.96 PGR (0.92) PGRARCHRM1LMNANR3C1
SCHEMBL6690848 0.91 PGR (0.83) PGRARCHRM1LMNANR3C1
SCHEMBL6695320 0.90 PGR (0.82) PGRARCHRM1LMNANR3C1
Mechlorethamine SCHEMBL28097486 0.89 PGR (0.79) PGRARCHRM1LMNANR3C1
SCHEMBL11303204 0.88 PGR (0.79) PGRARCHRM1LMNANR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 30436 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746898-A2 IDENTIFICATION OF SEQUENCE VARIANTS OF THE ERVMER34-1 SEQUENCE FAMILY AND USE IN ANTI-CANCER THERAPIES The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2026-05-27 EP claimed
EP-3607938-B1 PHARMACEUTICAL COMPOSITION SOVIC BRKICIC LJILJANA (HR) 2026-05-27 EP claimed
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
US-20260109699-A1 AZOLE DERIVATIVES AS SHP2 INHIBITORS IRBM S.P.A. (IT) 2026-04-23 US claimed
US-20260108476-A1 2,4 DNP and Prodrugs Thereof for Treatment of Cancer MITOCHON PHARMACEUTICALS, INC. (US) 2026-04-23 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
EP-4729519-A1 CRYSTAL FORM OF ENPP1 INHIBITOR CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) 2026-04-22 EP claimed
EP-4729063-A2 TREATMENT OF CANCER USING COENZYME Q10 COMBINATION THERAPIES BPGbio, Inc. (US) 2026-04-22 EP claimed
US-12582672-B2 Vanadium compositions and methods for treatment of cancer THE BROAD INSTITUTE, INC. (US) 2026-03-24 US claimed
EP-0472645-B1 OSMOTIC DOSAGE FORM ALZA CORPORATION (US) 1993-07-14 EP claimed
US-5225192-A Crosslinked, swellable polymer VECTORPHARMA INTERNATIONAL S.P.A. (IT) 1993-07-06 US claimed
EP-0336014-B1 PHARMACEUTICAL COMPOSITIONS WITH CONTROLLED RELEASE, AND A METHOD FOR THEIR PREPARATION VECTORPHARMA INTERNATIONAL S.p.A. (IT) 1992-06-24 EP claimed
EP-0474374-A1 Method for treatment of bone wasting diseases using a progestin ORTHO PHARMACEUTICAL CORPORATION (US) 1992-03-11 EP claimed
CN-1047974-A Compositions and methods for effecting contraception COHEN MICHAEL (NL) 1990-12-26 CN claimed
EP-0364944-A1 Poorly soluble medicaments supported on polymer substances in a form suitable for increasing their dissolving rate VECTORPHARMA INTERNATIONAL S.P.A. (IT) 1990-04-25 EP claimed
EP-0155934-B1 PHARMACEUTICAL COMPOSITIONS FOR TREATING ANDROGEN-RELATED DISORDERS IN HUMANS Duke University (US) 1989-12-06 EP claimed
CN-88101379-A Methods and compositions for effecting contraception 1988-10-05 CN claimed
EP-0010964-A1 Ravidomycin, process of preparation and pharmaceutical compositions containing same AYERST, MCKENNA AND HARRISON INC. (CA) 1980-05-14 EP claimed
US-4177269-A ANTITUMOR AGENTS AKTIEBOLAGET LEO (SE) 1979-12-04 US claimed