Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942052 | 0.91 | LMNA (0.49) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8942298 | 0.90 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8942180 | 0.89 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8942075 | 0.89 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8941975 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8942285 | 0.85 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8942144 | 0.84 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8942266 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8941921 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL8942023 | 0.82 | LMNA (0.51) | KDM4EALDH1A1HSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |