Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614660 | 0.91 | NR1I2 (0.37) | ALDH1A1CYP3A4CYP1A2CYP2C19GAA | |
| SCHEMBL27925711 | 0.86 | SMN1; SMN2 (0.44) | ALDH1A1CYP3A4CYP2D6POLBLMNA | |
| SCHEMBL4613138 | 0.85 | CYP1A2 (0.41) | ALDH1A1CYP3A4CYP1A2CYP2C19GAA | |
| SCHEMBL9550950 | 0.84 | LTA4H (0.38) | — | |
| SCHEMBL15422617 | 0.82 | POLB (0.42) | CYP1A2CYP2C19GAAPOLBCYP2C9 | |
| SCHEMBL9440336 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CYP1A2CYP2C19GAA | |
| SCHEMBL4612178 | 0.79 | SMN1; SMN2 (0.41) | TDP1TSHRALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL17175328 | 0.78 | ALDH1A1 (0.46) | TDP1TSHRALDH1A1GAAMAPT | |
| SCHEMBL10779364 | 0.78 | CYP3A4 (0.41) | TSHRMAPK1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL7192869 | 0.78 | KMT2A (0.59) | TSHRMAPK1GAAPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578711-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5541299-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5502171-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| EP-0042556-B1 | PROCESS FOR THE MANUFACTURE OF ALKYLHYDRAZONE CATIONIC DYES AND THEIR DYESTUFF BASES | BAYER AG (DE) | 1984-02-08 | — | — | EP | disclosed |
| US-4376728-A | Process for the preparation of cationic alkylarylhydrazone dyestuffs and color bases thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1983-03-15 | — | — | US | disclosed |
| EP-0042556-A2 | Process for the manufacture of alkylhydrazone cationic dyes and their dyestuff bases | BAYER AG (DE) | 1981-12-30 | — | — | EP | disclosed |