SCHEMBL8942166

SCHEMBL8942166

Cc1cc(=O)n(-c2ccc(S(=O)(=O)O)cc2Cl)[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.58
MAPT P10636 7/20 0.58
KDM4E B2RXH2 5/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
KMT2A Q03164 5/20 0.51
CASP6 P55212 1/20 0.51
GAA P10253 4/20 0.43
HTT P42858 3/20 0.43
MEN1 O00255 1/20 0.43
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 3/20 0.39
CA1 P00915 5/20 0.38
CA2 P00918 5/20 0.38
CA12 O43570 4/20 0.38
CA9 Q16790 4/20 0.38
RECQL P46063 1/20 0.38
KDM5A P29375 1/20 0.36
KDM2B Q8NHM5 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
CA7 P43166 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29665085 0.89 ALDH1A1 (0.58) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL8942310 0.89 ALDH1A1 (0.58) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL5444744 0.86 MAPT (0.49) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL696836 0.84 ALDH1A1 (0.46) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL11655396 0.83 ALDH1A1 (0.47) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL5447378 0.82 MAPT (0.46) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL11433868 0.82 ALDH1A1 (0.48) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL11443269 0.80 ALDH1A1 (0.43) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL11753792 0.79 MAPT (0.44) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL692667 0.79 MAPT (0.52) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP claimed
EP-0263951-B1 Disazo compounds and compositions containing them BASF LACKE & FARBEN (DE) 1994-06-15 EP claimed
US-4894094-A HEAT RESISTANT PRINTING INKS BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1990-01-16 US claimed
EP-0263951-A2 Disazo compounds and compositions containing them BASF Lacke + Farben AG (DE) 1988-04-20 EP claimed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP disclosed
US-5578711-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-11-26 US disclosed
US-5541299-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-07-30 US disclosed
US-5502171-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-03-26 US disclosed
EP-0446731-B1 Process for the manufacture of azo dyes BAYER AG (DE) 1995-05-03 EP disclosed
EP-0263951-B1 Disazo compounds and compositions containing them BASF LACKE & FARBEN (DE) 1994-06-15 EP disclosed
EP-0592907-A1 Pigment compositions for solvent and water-based ink systems and the methods for producing them HOECHST CELANESE CORPORATION (US) 1994-04-20 EP disclosed
US-5298535-A Monoazo and disazo pigments dispersed in metal salt of carboxylic acid polymer HOECHST CELANESE CORPORATION (US) 1994-03-29 US disclosed
EP-0012716-A1 Monochlorotriazine dyestuffs of the pyrazolone series, their preparation and their use for dyeing and printing textile materials CIBA-GEIGY AG (CH) 1980-06-25 EP disclosed
US-4180503-A FOR DYEING POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed
US-4144231-A Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4143033-A WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4137228-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed
US-4124581-A FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST BAYER AKTIENGESELLSCHAFT (DE) 1978-11-07 US disclosed
US-4045428-A Water-soluble reactive naphthylazonaphthyl dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 US disclosed
US-4029643-A Chromium containing azo dyes NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-06-14 US disclosed