Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942001 | 0.84 | KMT2A (0.45) | ALDH1A1KDM4EHPGDHSD17B10ADRB2 | |
| SCHEMBL8942257 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10TOP2B | |
| SCHEMBL9776043 | 0.81 | KMT2A (0.40) | ALDH1A1KDM4EHPGDHSD17B10ADRB2 | |
| SCHEMBL8941993 | 0.78 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10TOP2B | |
| SCHEMBL8941916 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10TOP2B | |
| SCHEMBL8941971 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10TOP2B | |
| SCHEMBL8942147 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10TOP2B | |
| SCHEMBL8942157 | 0.77 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10TOP2B | |
| SCHEMBL8942125 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL8942039 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |